Cloning dinosaurs, sabertooths, mammoths... etc

[Noooooooooo]

I just got the idea for cloning extinct animals. I did some research and I found some intersting stuff.


"...we should be able to reconstruct genes from animals such as the wooly mammoth, giant sloth, saber-toothed cat or even from tissues of the Tyrannosaurus rex..."

"We don't plan to turn house cats into saber tooth cats or create a Jurassic Theme Park anytime soon. But we do think this breakthrough has many applications yet to be discovered and we look forward to working with our colleagues to thoroughly examine all the possibilities"

^ Things I saw in a article connected with cloning extinct animals
Article - http://www.bio-medicine.org/biology-news/Dinosaur-DNA-3F-New-Patent-Covers-Degraded-DNA-recovery-116-1/



Mamooths- Could intact nuclei be extracted from mammoth cells, which will have been frozen for at least 10,000 years at relatively high sub-zero temperatures? Food in a domestic freezer has a limited storage time based on changing texture and taste. What about a mamooth being frozen more than 100 centuries?

Dinosaurs&sabertooths - I do think it is possible to clone them but we simply do not have any DNA to reconstruct the genome of a dinosaur or saber (or any other extinct animals which we only have their bones left) - Bone marrow and blood, the best parts of an animal to get DNA from don't survive the fossilisation process to provide the complete sequence of DNA required (although some scientists claim to have extracted fragments of DNA from the long bones (legs) of dinosaurs).
If they could get good DNA from a fossil,which they can't cause it's a fossil and they had the proper technology then yeah they probably could.

What is your oppinion on this? Do you think It's possible?

[Sith Lord 13]

They can get DNA from mosquito type insects preserved in amber.

[Noooooooooo]

They can get DNA from mosquito type insects preserved in amber.

^ Good logic. I forgot about amber+insects part.
I remember reading somewhere that some scientists have managed to extract DNA from an extinct bee which was preserved in amber dated at 40 million years.

[Spook]

They can get DNA from mosquito type insects preserved in amber.


I heard this too. These are the mosquitos that were around at the time of the wooly mammoths, and if they extract the blood, some cells are left over from the mammmoth, and they think that they can reconstruct an organism.

Here's my answer to the original question in this thread- Yes, I think it is possible. I think anything is possible if we put our minds to it, but I think that it will take a vary, very long time.

I still don't understand how a whole organism can be constructed with a bit of blood, I mean, how are they supposed to reform skin and organs with that? It seems almost impossible, but scientists can do wonders! :D

[embers]

They can get DNA from mosquito type insects preserved in amber.

Funny how nobody got the Jurassic Park reference there. Damn, people these days.

[Noooooooooo]

I heard this too. These are the mosquitos that were around at the time of the wooly mammoths, and if they extract the blood, some cells are left over from the mammmoth, and they think that they can reconstruct an organism.

I still don't understand how a whole organism can be constructed with a bit of blood, I mean, how are they supposed to reform skin and organs with that? It seems almost impossible, but scientists can do wonders! :D

There are 2 types of cloning.
1st one is done using a technique called nuclear transfer.
To do this a somatic cell is taken from the animal and the nucleus is tranferred into a an oocyte ( an oocyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction-In other words, it is an immature ovum, or egg cell) that has had its nucleus removed. A low percentage of oocytes will then begin to divide and will develop into an animal. Because the oocyte is pluripotent (retains the ability to form all tissues of the animal as well as all supportive tissues such as the placenta and umbilical cord, in mammals) instead of totipotent (only able to differentiate into the animals tissues) it can be succesfully implanted into a female. This female is unable to produce oocytes herself but can support an embyro/fetus.

2nd type of cloning- Induced Pluripotent stem cells (IP cells): Newer techniques involve changing a cell from a somatic cell (often fibroblast) into a stem cell by transducing four factors (either by RNA transduction or protien transduction). This method has yielded mice that are fertile and live a normal life span (dolly did not due to telomerase induce issues) and have wild type cancer rates (animals which are cloned using somatic nuclear transfer also dont show higher than normal rates of cancer).

Simply said -
Firstly an egg is taken from a female ,the nucleus is then removed and replaced by a diploid nuclei from the animal you want to clone. This is then allowed to divide in vitro up to a certain size and is then placed in the womb of a surrogate mother (usually the animal the egg was taken from). Then hopefully the embryo will grow and come to term.

In the case of cloning a mammoth the surrogate mother will probably be a elephant.

[Sage]

We should clone these beasts and raise them on farms to be processed into delicious meat that could feed people. Mammoths are huge, man. And probably tasty.

[Noooooooooo]

We should clone these beasts and raise them on farms to be processed into delicious meat that could feed people. Mammoths are huge, man. And probably tasty.

Hell yeah! Thats what I'm thinking! It's the only use we can have of em.

[Peace God]

We should clone these beasts and raise them on farms to be processed into delicious meat that could feed people. Mammoths are huge, man. And probably tasty.
I doubt i'd find it tasty but I'd would definitely have to try it just to say I did. I mean come on its mammoth and dinosaur meat...who the hell could turn that down?

[Iceman]

You know the Russian's are working on cloning the mammoth?

[Sage]

I mean come on its mammoth and dinosaur meat...who the hell could turn that down?

Vegetarians.

[Peace God]

Vegetarians.
But I am a vegetarian. :P I'd still eat it though just to say I ate a motherfuckin' dinosaur. I would definitely need to know what a T-Rex or a wooly mammoth tastes like.

[Sage]

But I am a vegetarian.

But you are not vegetarians.